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Nilvadipine may slow down Alzheimer’s disease

Researchers have discovered that nilvadipine, a drug that docs often use to deal with hypertension, might assist people with Alzheimer’s disease by increasing blood flow to the brain.

Alzheimer’s disease is the most occurring type of dementia. This progressive dysfunction causes the degeneration and, finally, the death of mind cells.

Individuals with dementia experience cognitive decline, and have issues making judgments and performing everyday tasks.

Dementia impacts thousands of individuals worldwide. Based on Alzheimer’s Disease International, the number of people with dementia was near 50 million in 2017, and the organization says this number will virtually double every 20 years, reaching 75 million individuals by 2030. In the USA, Alzheimer’s disease is the sixth leading cause of death. Researchers have been looking for remedies to slow the development of the dysfunction and not too long ago discovered that hypertension drug nilvadipine might have constructive results on the cerebral blood circulation of those with Alzheimer’s illness. The outcomes seem within the journal Hypertension.

Nilvadipine is a calcium channel blocker that leads to vascular rest and lowers blood pressure, and other people typically use it to deal with hypertension. The objective of the latest study, which included 44 participants with mild to reasonable Alzheimer’s illness, was to seek out out whether or not nilvadipine might slow the development of the disorder.

The researchers randomly gave nilvadipine or a placebo to the individuals and requested them to continue the therapy for six months. They measured the blood flow to particular areas of the brain, utilizing a unique MRI approach, at the beginning of the research and after six months